Nov 12, 2019  
2018-2019 University Catalog 
2018-2019 University Catalog [ARCHIVED CATALOG]

PVM - 553 Observational Epidemiology

Course will provide an in-depth description of case- control and cohort studies. This includes: the different types (e.g. hospital- or population-based controls, retrospective and prospective cohorts, nested case- control), their strengths, weaknesses and uses, the definition and selection of cases and controls, matching and sampling, the definition and selection of exposure and comparison groups, the ascertainment of disease status and exposure status, and issues in analysis and interpretation of data, including the role of bias (selection bias, confounding bias, recall bias, misclassification of disease and exposure status), the effect of non-participation and loss to follow-up, and the application of various analytic approaches (stratification, standardization, and multivariate models). The computation, interpretation and application of basic epidemiologic concepts and statistics will be reinforced throughout the course, including measures of disease frequency (prevalence, incidence, attack rate) and measures of association (relative risk, odds ratio, risk difference, population attributable risk). Landmark studies illustrating the different types of case-control and cohort studies will be described. Trainees will be assigned readings from basic epidemiologic texts as well as publications from major case-control and cohort studies. Retake Counts for Credit: Yes. Pass/No Pass Grading Allowed: No. Credit(s): 1